Science & Technology

One of the paths explored to obtain compositions rich in selenium consists in enriching certain microorganisms with organic selenium from inorganic selenium. These microorganisms, once enriched, can serve as dietary supplement for the preparation of food products. The microorganisms enriched with selenium  …

For some projects Tetrahedron uses the cell as a chemical factory thus limiting the energy and environment cost for the manufacturing of the final product. It was the case of the original molecule NutraSelen which has been designed as a physiological precursor of L-selenomethioneine, the physiological  …

Any Tetrahedron’s project starts from the analysis of an unbalanced physiological situation with the objective to restore the homeostasis of the cells. Since Tetrahedron is focused on the oxidative stress situation the goal is to restore the redox homeostasis by activating our own Antioxidant Defense  …

While ozone depletion and sun exposure make us prone to UV overexposure, the benefits of sunlight, such as vitamin D production and mood boosting, are overwhelmed by its deleterious effects on skin. Solar erythema, photo-dermatosis, photo-aging and skin cancers are well-documented examples of such effects.  …

To cope with oxidative stress, skin is endowed with antioxidant defenses which prevent from ROS- and RNS-mediated alterations or damage. However, antioxidant defenses have been shown to be depleted following UVA irradiation. The activation of the « master » transcription factor Nrf2 appears to play  …

Halliwell et al. published recently an excellent and complete review on L-ergothioneine (Halliwell, B. Cheah, I. and Tang, R.; 2018). L-ergothioneine cannot be synthesized by humans and therefore is available only from dietary sources. The normal presence of L-ergothioneine in almost all the tissues,  …

Revisiting the Antioxidant (AOX) Concept … Direct anti-oxidation is a purely chemical concept: reaction of one oxidant molecule with one reductive (antioxidant) molecule. Such a chemical reaction is non-controlled: as soon as the oxidant and the antioxidant are in touch the reaction takes place.  …